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Title of Paper: Serologic prevalence of antibodies to Helicobacter pylori in internationally adopted children.

Type of Paper: Original Article; Medical Chart Review

Purpose: To determine the prevalence of and the risk factors for Helicobacter pylori (H. pylori ) in internationally adopted children

Nutrition-Related Measures:

Participants: 226 international adoptees between the ages of 4 months and 16 years at adoption. Children were adopted from 18 countries. The majority (70%) came from Russia, Romania, or China. Of those with pre-adoption information, 66% were institutionalized since birth, 12% lived in foster care, and the remaining children lived in a variety of settings prior to adoption

Methods: Chart review of routine medical evaluations completed at one international adoption clinic soon after arrival into the U. S. All children who had routine laboratory testing completed at one international adoption during a two-year period were included.

Nutrition Results:

Conclusions & Clinical Implications: Nearly one-third (31%) of the international adoptees were H. pylori -positive. H. pylori was associated with being in institutional care, older age at adoption, and infections with other intestinal parasites. Previous studies in other populations of children have reported an increase in malnutrition, including anemia, diarrhea, and growth failure, in those with H. pylori or other parasitic infections. However, there were no such associations between H. pylori or other parasitic infections and malnutrition in this sample of international adoptees. The authors suggest that these associations were not found because H. pylori infection is just one of the many risk factors for malnutrition in international adoptees.

Limitations of the Nutritional Results: The only marker used to identify anemia was hematocrit, and it was not reported whether the anemia was due to iron deficiency or another etiology.

Reference: Miller LC, Kelly N, Tannemaat M, Grand RJ. Serologic prevalence of antibodies to Helicobacter pylori in internationally adopted children. Helicobacter. 2003; 8 (3): 173-178. http://www.ncbi.nlm.nih.gov/pubmed/12752728


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